David Letterman has vented his frustration at the arguments against same-sex marriage as the issue continues to dominate headlines.

Last week, the US Supreme Court held two days of oral arguments on marriage equality issues.

David Letterman sat down with gay MSNBC news anchor Rachel Maddow earlier this week to discuss the cases and was not shy about discussing his dislike of anti-gay discrimination.

“I’m just sick and tired, and I think it has really crossed the line of being nonsense,” he said to Maddow.

“This ongoing, politically nuanced, religiously nuanced discussion of gay marriage, gay rights. It is absolute stupidity.

“Humans have the right to do what humans do, that’s it. End of  story. There’s no argument. There’s no exceptions. Humans have rights and they get to do what humans get to do. Case closed. Good night.”